This study developed a computer-assisted music therapy based on somatic vibrational music for the mental subhealth state of college students. Low-frequency signal waves were used for sonic intervention, and the sound source and amplification-crossover-transducer device were designed. Exploratory factor analysis was utilized to screen the emotional word items of the scale, and the scale was revised. Combining the biofeedback instrument with the revised PANAS-R scale, a multimodal assessment system was constructed. All subjects showed significant positive elevation (p<0.05) in the positive mood dimension after the experiment, and the trend of heart rate in the control group was roughly similar to that of the experimental group, but the magnitude of change was not as large as that of the experimental group. The results of the paired-samples t-test showed that the heart rate of the control group showed a significant decrease only in the acquisition stage 3 of the experiment, while the heart rate of the experimental group showed a significant decrease in the acquisition stages 3, 4, 5 and 6. The computer-assisted music therapy proposed in this paper can effectively alleviate the anxiety cycle, providing a technical path with both scientific and humanistic features for psychological intervention in the perspective of cultural education.
