Uneven regional economic development is caused by factors such as resource endowment, geographic location, and policy preferences between regions, and is particularly evident within China. This paper discusses the application of the total revenue – total expenditure model and the theory of the multiplier effect of fiscal policy in the study of the relationship between high-quality regional economic development and fiscal policy. China is divided into four regions: east, west, central, and northeast, and a panel regression model is constructed on the basis of discussing differences in regional economic development levels. The model takes regional GDP as the explanatory variable, and general public budget expenditure and total fixed asset investment as the explanatory variables, while setting relevant control conditions. Person’s correlation analysis shows that all the variables show a significant correlation with each other at the 5% level. The Hausman test of the structural model for the four regions rejects the original hypothesis at the 1% significance level, accepting the model as a fixed-effects variable-intercept form. The overall fitting effect of the model is good, and it can clearly reveal the mechanism of the impact of macro-fiscal policy regulation on the economic development of different regions.
