The competitive level of modern table tennis is constantly improving, and the scientific assessment of athletes’ technical and tactical abilities has become a key link to improve the training effect and game performance. In this paper, a multivariate statistical analysis method was used to construct a comprehensive strength assessment model for the technical and tactical abilities of high-level table tennis players. The study selected 155 singles matches of the world’s top 20 male and female offensive players as the research samples, extracted the four main tactical factors of holding ability, serving scoring efficiency, stability and breaking ability by using factor analysis, and established a multiple linear regression model to assess the probability of winning. The results of the study showed that the KMO value was 0.698, the cumulative variance contribution of the four male factors amounted to 66.439%, and the coefficient of determination of the multiple regression equation, R², was 87.1%, which indicated that the tactical factors could explain 87.1% of the reasons for the changes in the probability of winning. Pass-through analysis revealed that there was an interaction effect among the tactical factors, and the direct pass-through coefficients were ranked as serve scoring efficiency (0.523), holding ability (0.522), stability (0.427), and breaking ability (0.246). The model validation showed that the overall technical and tactical indicators of men’s singles were better than those of women’s singles, and the scores of the holding ability factor were 0.652 and 0.759, respectively. The assessment model constructed in this study can objectively quantify the differences in the technical and tactical levels of the athletes and provide data support for the scientific training and game strategy development.